First Trial Of Once-Daily Male Birth Control Pills Deemed A Success

First Trial Of Once-Daily Male Birth Control Pills Deemed A Success

According to a report from the Telegraph, the pill contains a drug known as dimethandrolone undecanoate (DMAU), which differs from other similar drugs before it due to the inclusion of a long-chain fatty acid that allows it to metabolize at a slower pace, meaning it should only be taken once a day instead of twice.

"DMAU is a major step forward in the development of a once-daily 'male pill, '" Page said.

While this research is not as far progressed as the new DMAU study, it highlights the variety of different tactics scientists are investigating to develop an elusive male contraceptive pill. "Despite testosterone levels that were very low, the men had no symptoms", Page said. Researchers say longer term studies are now underway to confirm that the pill can block sperm production so a man cannot get his partner pregnant.

A total of 100 healthy men aged 18 to 50 took part in the clinical trials for the male contraceptive, which were conducted by researchers from the University Washington Medical Center, with 83 of them staying on until the end of the study. It is being developed with funding from the National Institutes of Health. Men can also have a vasectomy, but this method is invasive and often not reversible.

However, all the men taking the male pill had weight gain and a drop in their HDL or good cholesterol levels. The men took the contraceptive or a placebo once a day for 28 days with food. Maybe the study that begins in April will present us encouraging findings as well as the one presented at ENDO 2018, the Endocrine Society's 100th annual meeting in Chicago, on Sunday.

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There's a new contraceptive in town (well, not now, but possibly soon) and it aims to put the responsibility of safe sex square in the hands of men.

A daily pill for males has always been elusive to pharmaceutical developers, as oral testosterone in previous forms may damage the liver or clear the body too quickly to work in just one pill per day. The researchers said in order for the pills to be effective, they must be taken with food.

At the highest dose of DMAU tested, 400 mg, participants showed "marked suppression" of levels of their testosterone and two hormones required for sperm production. Apparently, researchers are close to developing male birth control pills along the lines of oral contraception that's been available for women since the 1960s.

"There has been very nice work in this area demonstrating that men across the globe - various races, ethnicities and across socioeconomic groups - are actually very interested in contraception", she added.

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